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KMID : 0366220170520010065
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Korean Journal of Hematology
2017 Volume.52 No. 1 p.65 ~ p.67
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Hypercalcemia, multiple osteolytic lesions, and acute renal failure: a rare presentation of B-cell acute lymphoblastic leukemia
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Puri Vandana
Sharma Pooja
Gopalakrishnan Sundaram
Sikka Meera
Avasthi Rajnish
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Abstract
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TO THE EDITOR: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy [1]. Anemia, hepatosplenomegaly, and generalized lymphadenopathy are common findings in B-cell ALL [2]. Although bone pain is a common symptom of being in almost 40% of cases, hypercalcemia and frank osteolytic lesions are very rare in ALL [34]. Additionally, while about 7% of cases are diagnosed as the kidney involvement of ALL by intravenous pyelogram, it is uncommon that acute renal failure presents these primary manifestations [56]. We report a rare case of B-ALL with prominent ostalgia and impaired kidney functions.
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